BLASTP 2.2.26 [Sep-21-2011] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= AA650_17280 cysteine desulfurase (382 letters) Database: GCA_000316115.1P 7828 sequences; 2,521,536 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Lepto7375DRAFT_4103 cysteine desulfurase family protein 510 0.0 Lepto7375DRAFT_2148 cysteine desulfurase NifS 250 2e-79 Lepto7375DRAFT_5569 cysteine desulfurase family protein 246 5e-78 Lepto7375DRAFT_3255 cysteine desulfurase-like protein, SufS subf... 86 5e-19 Lepto7375DRAFT_1231 cysteine desulfurase family protein, VC1184 ... 66 2e-12 Lepto7375DRAFT_3829 selenocysteine lyase 56 2e-09 Lepto7375DRAFT_3365 selenocysteine lyase 47 2e-06 Lepto7375DRAFT_4236 serine-pyruvate aminotransferase/archaeal as... 35 0.014 Lepto7375DRAFT_5152 PLP-dependent enzyme, glutamate decarboxylase 33 0.044 Lepto7375DRAFT_6010 nucleoside-diphosphate-sugar epimerase 30 0.48 2f0d5c320b36a160daef6581caca6f4a >Lepto7375DRAFT_4103 cysteine desulfurase family protein Length = 394 Score = 510 bits (1314), Expect = 0.0, Method: Compositional matrix adjust. Identities = 252/384 (65%), Positives = 305/384 (79%), Gaps = 4/384 (1%) Query: 1 MQVYLDYSATTPTRPEAIAIIQTILTQQWGNPSSLHEWGNRAALILETARMQVAGLINAV 60 MQ+YLDYSATTP R E +A + + + WGNPSSLH WG+RAA ++ETARMQVA L+ A Sbjct: 1 MQIYLDYSATTPPRAEVMAAMGSAMKHSWGNPSSLHNWGSRAATVMETARMQVADLMGAS 60 Query: 61 PESIIFTSGGTEADNLAIMGVARCYTTPQHMIISSVEHSAISEPAKMLENWGWEITRLGV 120 ++++FT+ GTEA+NLAIMGVA+ Y P+HMIIS+VEHSAI++P +LE WGW+ITRL V Sbjct: 61 GDAVVFTASGTEANNLAIMGVAQQYRKPRHMIISAVEHSAIAKPITLLEQWGWQITRLPV 120 Query: 121 NHQGRVNPEDLKAALRHNTVLVSVIYGQSEIGTVQPIAELGKITKTHG----ALFHTDAV 176 + G+V+P DL ALR +TVLVSVIYGQSE+GT+QPI EL + K LFH+DAV Sbjct: 121 DSYGQVHPIDLAQALREDTVLVSVIYGQSEVGTIQPITELAAVIKASDHISTPLFHSDAV 180 Query: 177 QVAGRLPLDVQTLPVDLLSLSSHKLYGGLGAGALYLRPGVELMPLLGGGGQENGLRSGTQ 236 QVAGRLP+DVQ L VDLLS+SSHKLYG GAGALY++PG +LMPL+ GGGQEN LRSGTQ Sbjct: 181 QVAGRLPIDVQKLGVDLLSISSHKLYGPQGAGALYVKPGTDLMPLINGGGQENHLRSGTQ 240 Query: 237 ATPAIAGFGVAAELAAQELETETGRLILLRDRLFAILADVPGLIPTGDKIHRLPHHLSFY 296 A P I GFGVAAELA QEL E RL+ LRDRL L P L+ TG RLPHH+SFY Sbjct: 241 AVPTIVGFGVAAELARQELSQEQQRLLKLRDRLIEQLQCHPELLLTGHPQQRLPHHVSFY 300 Query: 297 LEAADGEKISGKTLVRQLNLAGIGISAGAACNSGKLSPSPILLAMGYSQKAALGGIRLTL 356 L A+GE++SGKTLVRQLNLAGIGISAG+AC+SGKL+PSPIL AMG+S AA GIRLTL Sbjct: 301 LPNANGEQVSGKTLVRQLNLAGIGISAGSACHSGKLTPSPILQAMGFSNIAAKTGIRLTL 360 Query: 357 GKQTTAADIDWTGIVVKQILQRLI 380 G QTT AD+DWT +VV+QI++R++ Sbjct: 361 GHQTTEADVDWTAMVVRQIIERVM 384 >Lepto7375DRAFT_2148 cysteine desulfurase NifS Length = 397 Score = 250 bits (639), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 147/380 (38%), Positives = 215/380 (56%), Gaps = 7/380 (1%) Query: 1 MQVYLDYSATTPTRPEAIAIIQTILTQQWGNPSSLHEWGNRAALILETARMQVAGLINAV 60 M +YLD +ATT P+ + + L+ +GNPSS+H +G + ++ AR++VA L+ A Sbjct: 1 MVIYLDNNATTRVDPDVLDAMLPYLSDLYGNPSSMHSFGGQVGAAIQDARVRVAELLGAE 60 Query: 61 PESIIFTSGGTEADNLAIMGVARCYTTPQHMIISSVEHSAISEPAKMLENWGWEITRLGV 120 IIFTS G+E +N AI +H++ ++VEH AI K LE G+ +T L V Sbjct: 61 DTEIIFTSCGSEGNNTAIHAALAVQPEKRHIVTTAVEHPAILNVCKHLEKKGYTVTYLSV 120 Query: 121 NHQGRVNPEDLKAALRHNTVLVSVIYGQSEIGTVQPIAELGKITKTHGALFHTDAVQVAG 180 + +G+++ +++AA+ T LV+ +Y +E G + PI ++G I K GA FH DAVQ G Sbjct: 121 DRRGQLDLMEVEAAMTGGTALVTTMYANNETGVIFPIEQIGAIAKECGATFHVDAVQAVG 180 Query: 181 RLPLDVQTLPVDLLSLSSHKLYGGLGAGALYLRPGVELMPLLGGGGQENGLRSGTQATPA 240 +LP+D++ +DLL+LS HKL+ G GALY+R G P L GG QE G R+GT P Sbjct: 181 KLPIDLKNSTIDLLTLSGHKLHAPKGVGALYVRRGFRFRPFLLGGHQERGRRAGTHNVPG 240 Query: 241 IAGFGVAAELAAQELETETGRLILLRDRLFAILAD-VPGLIPTGDKIHRLPHHLSFYLEA 299 I G AAE+A + L R LRD+L + L + +P G RLP+ + + Sbjct: 241 IIALGKAAEVAREHL-AAVHRERQLRDQLESQLLELIPDCDVNGGGTPRLPNTTNIGFKY 299 Query: 300 ADGEKISGKTLVRQLNLAGIGISAGAACNSGKLSPSPILLAMGYSQKAALGGIRLTLGKQ 359 +GE I + LN GI S+G+AC SG L PS +L AMG G IR +L + Sbjct: 300 IEGEAI-----LFMLNQHGICASSGSACTSGSLDPSHVLTAMGLPYTILHGSIRFSLSRF 354 Query: 360 TTAADIDWTGIVVKQILQRL 379 TTA DI V+ I+++L Sbjct: 355 TTAEDIQQVVNVMPGIVEKL 374 >Lepto7375DRAFT_5569 cysteine desulfurase family protein Length = 383 Score = 246 bits (629), Expect = 5e-78, Method: Compositional matrix adjust. Identities = 153/381 (40%), Positives = 223/381 (58%), Gaps = 10/381 (2%) Query: 3 VYLDYSATTPTRPEAIAIIQTILTQQWGNPSSLHEWGNRAALILETARMQVAGLINAVPE 62 +YLD ATTP + ++ T+ +GNPSS+H +G ++ +R ++ INA PE Sbjct: 6 IYLDCHATTPVDQRVVEVMLPFFTEHFGNPSSVHHYGWPVEAAIKKSRETISHSINAQPE 65 Query: 63 SIIFTSGGTEADNLAIMGVARCYTTP-QHMIISSVEHSAISEPAKMLENWGWEITRLGVN 121 I+FTSG TEA+NLAI GVA Y + +H+I EHSA+ +P + LE+ G+E+T L V Sbjct: 66 EIVFTSGATEANNLAIKGVAEAYFSHGKHIITVQTEHSAVLDPCRYLESLGFEVTYLPVE 125 Query: 122 HQGRVNPEDLKAALRHNTVLVSVIYGQSEIGTVQPIAELGKITKTHGALFHTDAVQVAGR 181 G ++ L+ A+R T+LVSV+ +EIG +QP+ E+G + + LFHTDA Q G+ Sbjct: 126 PDGLLSLPLLEKAIRPETILVSVMAANNEIGVLQPLKEIGALCQEREILFHTDAAQAIGK 185 Query: 182 LPLDVQTLPVDLLSLSSHKLYGGLGAGALYLR---PGVELMPLLGGGGQENGLRSGTQAT 238 +PLDVQ + + L+S+++HK+YG G GALY+R P V L L GGG E G+RSGT Sbjct: 186 VPLDVQAMNIHLMSMTAHKVYGPKGIGALYVRRRHPRVNLAAQLHGGGHERGMRSGTLYP 245 Query: 239 PAIAGFGVAAELAAQELETETGRLILLRDRLFAILADVPGLIPTGDKIHRLPHHLSFYLE 298 P I GF A ELA E+ E RL LR +L L +P G RLP +L+ Sbjct: 246 PQIVGFAKALELATAEMAVERERLTGLRSQLLTHLHQLPDSYLNGHPTQRLPGNLNMSFG 305 Query: 299 AADGEKISGKTLVRQLNLAGIGISAGAACNSGKLSPSPILLAMGYSQKAALGGIRLTLGK 358 DG+ +L+ L + + +S+G+AC+S +PS +L A+G S + A +R LG+ Sbjct: 306 GVDGQ-----SLLLGLQ-SVVALSSGSACSSASTAPSHVLKALGRSDQLAYASLRFGLGR 359 Query: 359 QTTAADIDWTGIVVKQILQRL 379 TT +I G V + +Q L Sbjct: 360 FTTEQEIHQVGQTVVETVQAL 380 >Lepto7375DRAFT_3255 cysteine desulfurase-like protein, SufS subfamily Length = 420 Score = 85.9 bits (211), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 101/366 (27%), Positives = 153/366 (41%), Gaps = 62/366 (16%) Query: 3 VYLDYSATTPTRPEAI--AIIQTILTQQWGNPSSLHEWGNRAALILETARMQVAGLINAV 60 VY D +AT+ +P+ + A++ +H RA E R +VA INA Sbjct: 30 VYFDNAATS-QKPKVVLNALVDYYHQDNANVHRGVHTLSARATAAYEGTRDKVAAFINAS 88 Query: 61 PES-IIFTSGGTEADNLAIM--GVARCYTTPQHMIISSVEHSAISEPAKML-ENWGWEIT 116 + I+FT +EA NL G++ + +I+S +EH + P +++ E G + Sbjct: 89 SRNEIVFTRNASEAINLVAYAWGLSNLKAGDE-VILSVMEHHSNLVPWQLVAERTGAVLK 147 Query: 117 RLGVNHQGRVNPEDLKAALRHNTVLVSVIYGQSEIGTVQPIAELGKITKTHGALFHTDAV 176 + + + E K L T LV++ + + +G + P+ ++ K+ GA DA Sbjct: 148 HVQLTDTQEFDFEHFKELLCDRTRLVAINHISNTLGCINPVEDVIKLAHGQGAKVLIDAC 207 Query: 177 QVAGRLPLDVQTLPVDLLSLSSHKLYGGLGAGALYLRPGV--ELMPLLGGGG--QENGLR 232 Q +P+DVQ+L D L S HK+ G GAG LY + + + P LGGG Q+ L Sbjct: 208 QSVPHMPVDVQSLDCDWLVASGHKMCGPTGAGFLYGKLDILKAMPPFLGGGEMIQDVYLD 267 Query: 233 SGTQA---------TPAIAGF-----------GVAAELAAQELETETGRLILLRDRLFAI 272 T A TPAIA G+ + AQ E E R + R Sbjct: 268 HSTYAELPHKFEAGTPAIAEVIMLGAAVDYLTGIGMDRIAQ-YEHELTRYLYER------ 320 Query: 273 LADVPGLIPTGDKIHRLPHHLSFYLEAADG-----------EKISGKTLVRQLNLAGIGI 321 LADVP + G K ADG E + + L L+ GI I Sbjct: 321 LADVPKIKLYGPK------------PKADGSGRAAIATFTVENLHAQDLSTFLDQTGIAI 368 Query: 322 SAGAAC 327 +G C Sbjct: 369 RSGHHC 374 >Lepto7375DRAFT_1231 cysteine desulfurase family protein, VC1184 subfamily Length = 427 Score = 66.2 bits (160), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 62/278 (22%), Positives = 114/278 (41%), Gaps = 30/278 (10%) Query: 25 LTQQWGNPSSLHEWGNRAALILETARMQVAGLINAVPESIIFTSGGTEADNLAIMGVARC 84 LT N R ++ AR +A + P I+F + T + Sbjct: 59 LTHSNANAHGAFATSQRTDEVIAAARGAMADFLGCNPNEIVFGANMTSLTFAISRAIGHA 118 Query: 85 YTTPQHMIISSVEHSAISEPAKMLENWGWEITRLGVNHQG-RVNPEDLKAALRHNTVLVS 143 ++++ ++H A P L G + + ++ + ++ +DL + L H T L++ Sbjct: 119 LLPGDEILVTCLDHDANIAPWLALREQGIIVHTVDIHPENCTLDLKDLISKLNHRTRLLA 178 Query: 144 VIYGQSEIGTVQPIAELGKITKTHGALFHTDAVQVAGRLPLDVQTLPVDLLSLSSHKLYG 203 + Y + +GT+ + + ++ GA + DAV A P+DVQ L D L S +K +G Sbjct: 179 ITYASNAVGTLNDLPTIIQLAHNAGAWVYIDAVHYAAHGPIDVQQLDCDFLVCSPYKFFG 238 Query: 204 GLGAGALY-------------LRPGVELMPLLGGGGQENGLRSGTQATPAIAGFGVAAEL 250 G LY +RP +++P +GTQ +AG A E Sbjct: 239 P-HMGVLYGKRDHLERLHPYKVRPASDVIPY--------RWETGTQNHEGLAGVTAAIEY 289 Query: 251 AAQELETETGRLI--LLRDRLFAILADVPGLIPTGDKI 286 A + GRL+ + R A+ A + + +G+++ Sbjct: 290 LA-----DLGRLVSPQMSKRRGAVFAAMTAIRHSGEQL 322 >Lepto7375DRAFT_3829 selenocysteine lyase Length = 398 Score = 56.2 bits (134), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 60/233 (25%), Positives = 99/233 (42%), Gaps = 18/233 (7%) Query: 4 YLDYSATTPTRPEAIAIIQTI-LTQQWGNP--SSLHEWGNRAALILETARMQVAGLINAV 60 Y +Y P A+ IQ T Q P S+++ W E R +A + Sbjct: 20 YFNYGGQGPMVLNALKAIQFAHQTMQTRGPFGSAVNTWMQVEG---EKTRRVLADELGVS 76 Query: 61 PESIIFTSGGTEADNLAIMGVARCYTTPQHMIISSVEHSAISEPAKMLENWGWEITRLGV 120 P++++ T T N+A+ G++ + H+++S EH I L+ +++ Sbjct: 77 PQTMVLTEDVTVGCNIALWGMS--WRNGDHILLSDCEHPGIFAAVYELQR-RFDLEVSIF 133 Query: 121 NHQGRVNPED----LKAALRHNTVLVSVIYGQSEIGTVQPIAELGKITKTHGALFH--TD 174 H ++N + +++ LR NT LV V + G V P+ E+ ++ +D Sbjct: 134 PHLSQINMANPVAMIQSQLRPNTRLVVVSHVLWNTGQVMPLTEICQLCHAQPQTVRVLSD 193 Query: 175 AVQVAGRLPLDVQTLPVDLLSLSSHKLYGG-LGAGALYLRPGV--ELMPLLGG 224 A Q G LPL + VD + + HK G G G LY+ P EL P G Sbjct: 194 AAQSVGMLPLQMAETGVDFYAFTGHKWCCGPAGLGGLYVSPAAMEELAPTFIG 246 >Lepto7375DRAFT_3365 selenocysteine lyase Length = 343 Score = 46.6 bits (109), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 42/161 (26%), Positives = 72/161 (44%), Gaps = 5/161 (3%) Query: 46 LETARMQVAGLINAVPESIIFTSGGTEADNLAIMGVA--RCYTTPQHMIISSVEHSAISE 103 ++ A Q+A +N + + F G + NL ++ A + +I+S+ +H A + Sbjct: 1 MDEAYCQLAAYLNVSEDDVHF--GPSTTQNLYVLAHAFREIWNEGDEIILSNQDHEANAG 58 Query: 104 PAKMLENWGWEITRLGVNHQ-GRVNPEDLKAALRHNTVLVSVIYGQSEIGTVQPIAELGK 162 + LE G I + + GR+NP+ L L T L++ + + IG P+AE+ Sbjct: 59 FWRRLEKTGIVIKEWRIAPETGRLNPDHLDTLLSDRTRLLAFPHCSNVIGHTNPVAEIVS 118 Query: 163 ITKTHGALFHTDAVQVAGRLPLDVQTLPVDLLSLSSHKLYG 203 KT D V A D+ L VD+ S +K +G Sbjct: 119 KVKTADICVVVDGVAHAPHGLPDIGALGVDIYLFSLYKTWG 159 >Lepto7375DRAFT_4236 serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Length = 386 Score = 35.0 bits (79), Expect = 0.014, Method: Compositional matrix adjust. Identities = 18/72 (25%), Positives = 36/72 (50%), Gaps = 1/72 (1%) Query: 130 DLKAALR-HNTVLVSVIYGQSEIGTVQPIAELGKITKTHGALFHTDAVQVAGRLPLDVQT 188 +L+AAL H ++++++ ++ G QP+ +G + + L D V G +P+ + Sbjct: 141 ELRAALEEHRPAILALVHAETSTGARQPLEGVGDLCREFDCLLLVDTVTSLGGVPIFLDE 200 Query: 189 LPVDLLSLSSHK 200 VD+ S K Sbjct: 201 WKVDMAYSCSQK 212 >Lepto7375DRAFT_5152 PLP-dependent enzyme, glutamate decarboxylase Length = 482 Score = 33.5 bits (75), Expect = 0.044, Method: Compositional matrix adjust. Identities = 39/143 (27%), Positives = 59/143 (41%), Gaps = 21/143 (14%) Query: 52 QVAGLINAVPESI-IFTSGGTEADNLAIMGVAR--CYTTPQH---------MIISSVEHS 99 QVA L P++ + SGG+ A NL + VAR + H +S V H+ Sbjct: 134 QVAQLFGLGPQANGVLVSGGSLA-NLQALIVARNAAFNALDHGITQVKQPVFFVSEVAHT 192 Query: 100 AISEPAKMLENWGWEITRLGVNHQG-RVNPEDLKAALRH------NTVLVSVIYGQSEIG 152 + + A M+ G + HQ +++ DLK L + G + G Sbjct: 193 SFKK-AAMVMGLGTKAAIPVATHQNSQIDITDLKTKLTQAKANGQQPFAIVATAGTTVTG 251 Query: 153 TVQPIAELGKITKTHGALFHTDA 175 ++ PIAE+ I H FH DA Sbjct: 252 SIDPIAEMAHIANLHQLWFHVDA 274 >Lepto7375DRAFT_6010 nucleoside-diphosphate-sugar epimerase Length = 300 Score = 30.0 bits (66), Expect = 0.48, Method: Compositional matrix adjust. Identities = 21/51 (41%), Positives = 26/51 (50%), Gaps = 9/51 (17%) Query: 112 GWEITRLGVNHQGRVNPEDLKAALRHNTVLVSVIYGQS--EIGTVQPIAEL 160 G E+ R R +PEDLKAAL T IY + E+G QP+ EL Sbjct: 35 GVEVVRCD-----RKSPEDLKAALAGKT--FDAIYDNNGRELGDTQPLVEL 78 Database: GCA_000316115.1P Posted date: Aug 27, 2016 11:21 PM Number of letters in database: 2,521,536 Number of sequences in database: 7828 Lambda K H 0.318 0.135 0.394 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 7828 Number of Hits to DB: 1,935,994 Number of extensions: 82646 Number of successful extensions: 261 Number of sequences better than 1.0: 13 Number of HSP's gapped: 255 Number of HSP's successfully gapped: 13 Length of query: 382 Length of database: 2,521,536 Length adjustment: 90 Effective length of query: 292 Effective length of database: 1,817,016 Effective search space: 530568672 Effective search space used: 530568672 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 59 (27.3 bits)
0.982431647